The regenerative qualities of bone marrow have been used for decades and are considered the gold standard for stem cell harvesting. However, after the first 1-2 mL of bone marrow aspirate from a traditional needle, the number of total nucleated cells (TNC) in the aspirate drops dramatically due to the lower viscosity of blood and the design of the needle, which operates most optimally for small biopsy volume.
After aspirating the first 1-2 mL of bone marrow, peripheral blood will preferentially fill the vacated space, limiting the additional harvest of key stem and progenitor cells.
This ends in an expensive centrifuge system to spin the few extra cells from the blood.
With the Marrow Cellution™ Bone Marrow Aspiration System (MC-RAN-11) this issue is resolved by allowing the user to aspirate in a measured and controlled manner over a large geography inside the marrow space, while restricting peripheral blood infiltration.
The patented design allows for the closed tip needle to only draw laterally and after each harvest, a dial on the device is turned moving the needle up to the next point. This is continued until the needle falls out of the bone.
Cell Forming Units (CFU’s) were studied directly from the Marrow Cellution system and other traditional centrifuged samples. The graph below shows, even without a centrifuge, the concentration is considerably higher with Marrow Cellution:
As the kit only consists of the needle, this reduces costs and time. You have your cells immediately after harvest.
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